Publication, Publications Old vaccines for new infections: Exploiting innate immunity to control COVID-19 and prevent future pandemics
Preclinical, Publications The 3CLpro™ Inhibitor ALG-097111 Potently Inhibits SARS-CoV-2 Replication in Hamsters
Publication, Publications Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development
ALG-000184, Publications Safety, Tolerability and Pharmacokinetics of Single Ascending Doses of ALG-000184, a Class II Capsid Assembly Modulator for the Treatment of Chronic Hepatitis B (CHB), in Healthy Volunteers (HV)
ALG-000184, Publications Excellent preclinical characteristics of ALG-000184, a prodrug of the HBV capsid assembly modulator ALG-001075
Preclinical, Publications Structure-based discovery of potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitors using a multiplex screening platform
Publication, Publications Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)
ALG-055009 ALG-055009, a potent, selective THR-β agonist for treatment of NASH, demonstrates significant cholesterol reduction in a Diet-Induced Obese (DIO) mouse efficacy model
ALG-000184, Publications Best-in-class preclinical characteristics of ALG-000184, a prodrug of the capsid assembly modulator ALG-001075 for the treatment of chronic hepatitis B